A TRYPANOSOMAL ORTHOLOGUE OF AN INTERMEMBRANE SPACE CHAPERONE HAS A NON-CANONICAL FUNCTION IN BIOGENESIS OF THE SINGLE MITOCHONDRIAL INNER MEMBRANE PROTEIN TRANSLOCASE.

A trypanosomal orthologue of an intermembrane space chaperone has a non-canonical function in biogenesis of the single mitochondrial inner membrane protein translocase.

Mitochondrial protein import is essential for Trypanosoma brucei across its life cycle and mediated by membrane-embedded heterooligomeric protein complexes, which mainly consist of trypanosomatid-specific subunits.However, trypanosomes contain orthologues of small Tim chaperones that escort hydrophobic proteins across the intermembrane space.Here w

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Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury.

Prenatal inflammation is considered an important factor contributing to preterm birth and neonatal mortality and morbidity.The impact of prenatal inflammation on fetal bioenergetic status and the correlation of specific metabolites to inflammatory-induced developmental brain injury are unknown.We used a global metabolomics approach to examine plasm

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THE LEGAL PROTECTION OF THE PROPERTY RIGHT

The property right has been acknowledged as one of the personal fundamental rights since a very long time.It enjoys complete legal protection provided on the top of the national legislation hierarchy by constitutional norms as well as by juridical norms specific Fee to the various legal branches where the property is present.The property right is p

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THE LEGAL PROTECTION OF THE PROPERTY RIGHT

The property right has been acknowledged as one of the personal fundamental rights since a very long time.It enjoys complete legal protection provided on the top of the national legislation hierarchy by constitutional norms as well as by juridical norms specific Fee to the various legal branches where the property is present.The property right is p

read more